Recent research says that the answer to this question is an unequivocal “yes”.
More than one recent piece of research has highlighted the fact that anti-wrinkle injections actually make people feel better – and not just because they often increase self-esteem and self-image.
Interestingly, the reason for this was first suggested by Charles Darwin many, many years ago. He suggested that the muscles of facial expressions not only reveal our mood or emotional state, but also influence it.
Frowning is a negative expression, in that it is used to convey negative thoughts or emotions such as anger, fear and stress. Research shows that if a person is unable to frown, such as after anti-wrinkle injections, they are less able to maintain these negative emotions. This highlights the fact that the expressions on your face not only reflect the emotions that you feel in a positive or negative way – but also actively affect how you feel inside. This is certainly in keeping with the well understood principle that “Laughter is the best medicine”. Try it yourself – make yourself smile (go on – do it right now!) and generally you can feel your mood improve a little bit.
This research has led some experts to suggest that anti-wrinkle injections may be a useful adjunctive therapy for some patients with conditions such as depression.

Dr Christopher Leat